Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 9/20 | 0.42 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | SMURF1 | Q9HCE7 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 4/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | LPL | P06858 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28605702 | 0.86 | GPR119 (0.45) | LPLLIPG | |
| SCHEMBL28605632 | 0.85 | FFAR4 (0.44) | FFAR4DRD3EPHX2SMURF1ACACB | |
| SCHEMBL28605634 | 0.85 | FFAR4 (0.44) | FFAR4DRD3EPHX2SMURF1ACACB | |
| SCHEMBL28595539 | 0.80 | LIPG (0.49) | ACACBLPLLIPG | |
| SCHEMBL28918776 | 0.78 | BTK (0.49) | FFAR4DRD3 | |
| SCHEMBL28918773 | 0.78 | BTK (0.49) | FFAR4DRD3 | |
| SCHEMBL28614161 | 0.76 | ACACB (0.45) | ACACB | |
| SCHEMBL4444630 | 0.75 | LMNA (0.64) | — | |
| SCHEMBL28605624 | 0.74 | SMN1; SMN2 (0.53) | — | |
| SCHEMBL22186372 | 0.74 | PIM1 (0.47) | FFAR4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164461-A | Heterocyclic derivatives as Nav1.7 and Nav1.8 blockers | 拉夸里亚创药株式会社 | 2021-07-23 | — | — | CN | disclosed |