Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | PGR | P06401 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.35 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28606394 | 0.82 | MDM2 (0.40) | NPSR1LMNAPGRCFTRGOPC | |
| SCHEMBL181563 | 0.81 | CFTR (0.48) | NPSR1LMNACFTRGOPCMAPT | |
| SCHEMBL30074263 | 0.81 | CFTR (0.48) | NPSR1LMNACFTRGOPCMAPT | |
| SCHEMBL13020883 | 0.79 | PDK2 (0.46) | NPSR1LMNAPGRELANEMAPT | |
| SCHEMBL20901385 | 0.79 | PDK2 (0.46) | NPSR1LMNAPGRELANEMAPT | |
| SCHEMBL12306480 | 0.79 | PDK2 (0.46) | NPSR1LMNAPGRELANEMAPT | |
| SCHEMBL14462993 | 0.75 | S100A4 (0.42) | CFTRGOPCTDP1ALDH1A1MEN1 | |
| Propionic Acid SCHEMBL4796324 | 0.74 | PKM (0.41) | NPSR1LMNACFTRGOPCMAPT | |
| SCHEMBL14095186 | 0.73 | NPSR1 (1.00) | NPSR1LMNACFTRGOPCMAPT | |
| SCHEMBL6550908 | 0.73 | CFTR (0.41) | LMNACFTRGOPCMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109574818-B | Polysubstituted indanone derivative and preparation method thereof | 华侨大学 | 2021-08-03 | — | — | CN | disclosed |