Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13020883 | 1.00 | PDK2 (0.46) | PDK2PGRELANELMNANPSR1 | |
| SCHEMBL12306480 | 1.00 | PDK2 (0.46) | PDK2PGRELANELMNANPSR1 | |
| SCHEMBL20016023 | 0.85 | PGR (0.46) | PDK2PGRELANELMNANPSR1 | |
| SCHEMBL14462993 | 0.84 | S100A4 (0.42) | PDK2SMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL28606394 | 0.80 | MDM2 (0.40) | PGRELANELMNANPSR1MAPT | |
| SCHEMBL28610336 | 0.79 | NPSR1 (0.57) | PDK2PGRELANELMNANPSR1 | |
| SCHEMBL12306505 | 0.79 | PDK2 (0.51) | PDK2PGRLMNANPSR1ALDH1A1 | |
| SCHEMBL13597337 | 0.76 | PGR (0.39) | PDK2PGR | |
| SCHEMBL3368868 | 0.74 | PGR (0.69) | PGRELANEKDM4EHTTATM | |
| SCHEMBL13665805 | 0.72 | PDK2 (0.44) | PDK2ELANELMNANPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10263192-B2 | Organic electroluminescent device using aryl amine derivative containing heterocycle | IDEMITSU KOSAN CO., LTD. (JP) | 2019-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10263192-B2 | Organic electroluminescent device using aryl amine derivative containing heterocycle | SLC18A1, SLC18A2, AOC2 | PDK2 833/4885PGR 695/4885ELANE 2164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.