SCHEMBL28610377

SCHEMBL28610377

[CH2]c1c(C)oc2c(O)cccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 7/20 0.43
EGFR P00533 1/20 0.43
ATP1A1 P05023 2/20 0.42
ATP1B1 P05026 2/20 0.42
ATP1A3 P13637 2/20 0.42
ATP1B2 P14415 2/20 0.42
ATP1A2 P50993 2/20 0.42
ATP1B3 P54709 2/20 0.42
FXYD2 P54710 2/20 0.42
ATP1A4 Q13733 2/20 0.42
GAA P10253 2/20 0.38
LOXL2 Q9Y4K0 1/20 0.38
ACHE P22303 1/20 0.37
MAOB P27338 1/20 0.37
PTPN1 P18031 1/20 0.36
TRPA1 O75762 2/20 0.34
CYP1A2 P05177 2/20 0.34
MAPT P10636 2/20 0.34
RECQL P46063 2/20 0.34
APP P05067 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6454090 0.80 MAOA (0.46) MAOAEGFRATP1A1ATP1B1ATP1A3
SCHEMBL28604570 0.77 LOXL2 (0.38) MAOALOXL2MAOBCYP1A2
SCHEMBL5141096 0.74 ATP1A1 (0.59) MAOAEGFRATP1A1ATP1B1ATP1A3
SCHEMBL18827705 0.72 ATP1A1 (0.49) MAOAEGFRATP1A1ATP1B1ATP1A3
SCHEMBL22010749 0.70 CA2 (0.39) MAOAEGFRATP1A1ATP1B1ATP1A3
SCHEMBL28604517 0.70 ESR2 (0.39) GAAHPGDALOX15TSHRESR2
SCHEMBL10789961 0.69 ESR2 (0.53) MAOAEGFRATP1A1ATP1B1ATP1A3
SCHEMBL7228336 0.67 ATP1A1 (0.79) MAOAEGFRATP1A1ATP1B1ATP1A3
SCHEMBL5433276 0.67 MAOB (0.65) MAOAGAAMAOBCYP1A2MAPT
SCHEMBL24923419 0.66 MAOA (0.35) MAOAEGFRATP1A1ATP1B1ATP1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113272302-A Antibiotic compounds, process for their manufacture, pharmaceutical compositions containing them and their use 德彪药业国际股份公司 2021-08-17 CN disclosed