Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17007864 | 0.78 | TBXAS1 (0.41) | MAPTKMT2AALDH1A1POLBNPSR1 | |
| SCHEMBL27772056 | 0.75 | ABCB11 (0.47) | LMNAMAPTKMT2AMAOBL3MBTL1 | |
| SCHEMBL17018525 | 0.75 | NPSR1 (0.41) | LMNAMAPTKMT2AALDH1A1POLB | |
| SCHEMBL28544709 | 0.75 | LMNA (0.47) | LMNAMAPTKMT2AELANETP53 | |
| SCHEMBL29136986 | 0.74 | MAPT (0.46) | LMNAMAPTKMT2AMAOBL3MBTL1 | |
| SCHEMBL29879983 | 0.74 | MAPT (0.46) | LMNAMAPTKMT2AMAOBL3MBTL1 | |
| SCHEMBL10814021 | 0.74 | SCN5A (0.47) | LMNAMAPTKMT2AMAOBL3MBTL1 | |
| SCHEMBL1561435 | 0.72 | MAPT (0.46) | LMNAMAPTKMT2AMAOBL3MBTL1 | |
| SCHEMBL30914092 | 0.72 | MAPT (0.46) | LMNAMAPTKMT2AMAOBL3MBTL1 | |
| SCHEMBL9136154 | 0.72 | KCNN4 (0.51) | MAPTKMT2AELANEL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164448-A | Amino acid anilines as small molecule modulators of IL-17 | 利奥制药有限公司 | 2021-07-23 | — | — | CN | disclosed |