Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.66 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28619301 | 0.85 | TGM2 (0.61) | TGM2RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL28624100 | 0.85 | B3GNT2 (0.47) | TGM2RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL28627367 | 0.85 | TGM2 (0.47) | TGM2NPC1SMN1; SMN2TP53MEN1 | |
| SCHEMBL28620280 | 0.85 | TGM2 (0.61) | TGM2RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL28615912 | 0.85 | TGM2 (0.61) | TGM2RAB9ANPC1SMN1; SMN2CNR1 | |
| SCHEMBL28617369 | 0.85 | KMT2A (0.60) | TGM2NPC1SMN1; SMN2TP53MEN1 | |
| SCHEMBL28619644 | 0.85 | KMT2A (0.60) | TGM2NPC1SMN1; SMN2TP53MEN1 | |
| SCHEMBL28630813 | 0.85 | KMT2A (0.60) | TGM2NPC1SMN1; SMN2TP53MEN1 | |
| SCHEMBL28354065 | 0.84 | TAS1R3 (0.70) | TAS1R3TAS1R1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28617576 | 0.83 | TGM2 (0.66) | TGM2RAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109438279-B | Small molecule compound for overcoming EGFR drug-resistant mutation and preparation method and application thereof | 四川大学 | 2021-08-31 | — | — | CN | disclosed |