SCHEMBL28616609

SCHEMBL28616609

CC(O)C(=O)C1=CC(=O)NC1=O

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28229004 0.74 KMT2A (0.31)
SCHEMBL27775587 0.72 MAPT (0.32)
SCHEMBL6022461 0.70
SCHEMBL555854 0.66 GSR (0.43)
SCHEMBL1425299 0.64 PTGS2 (0.33)
SCHEMBL17924957 0.64
Butanol SCHEMBL28118465 0.63 TSHR (0.39) KDM4E
Acetic Acid SCHEMBL28734535 0.62
SCHEMBL17924947 0.62 MAOA (0.31)
SCHEMBL3173595 0.62 TSHR (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113975406-A Glycoengineered antibody drug conjugates 建新公司 2022-01-28 CN disclosed
CN-108025083-B Glycoengineered antibody drug conjugates 建新公司 2021-09-03 CN disclosed