SCHEMBL28616802

SCHEMBL28616802

COc1ccc2[nH]cc([Se]C#N)c2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 2/20 0.53
HTR2B P41595 5/20 0.50
CYP1A2 P05177 3/20 0.50
MAPT P10636 3/20 0.50
ALDH1A1 P00352 2/20 0.50
TSHR P16473 2/20 0.50
KDM4E B2RXH2 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
CYP2C19 P33261 1/20 0.50
GFER P55789 1/20 0.50
HSD17B10 Q99714 1/20 0.50
HTR2A P28223 6/20 0.48
HTR2C P28335 5/20 0.48
HTR1A P08908 3/20 0.48
CYP2D6 P10635 2/20 0.48
HTR1D P28221 2/20 0.48
HTR1B P28222 2/20 0.48
HTR7 P34969 2/20 0.48
HTR6 P50406 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28631910 0.76 CSNK2A1 (0.54) GPR84HTR2BCYP1A2MAPTMEN1
SCHEMBL1778261 0.76 GPR84 (0.57) GPR84HTR2BCYP1A2MAPTALDH1A1
SCHEMBL28627511 0.76 SLC6A4 (0.46) HTR2AHTR1AHTR1BHTR6
SCHEMBL5432612 0.73 GPR84 (0.66) GPR84HTR2BCYP1A2MAPTALDH1A1
SCHEMBL31490955 0.73 TUBB4A (0.56) GPR84HTR2BCYP1A2MAPTALDH1A1
SCHEMBL2724551 0.73 GPR84 (0.69) GPR84HTR2BCYP1A2MAPTTSHR
SCHEMBL28616801 0.73 NR4A2 (0.45) ALDH1A1KDM4ENR4A2
SCHEMBL736956 0.72 GPR84 (0.64) GPR84HTR2BCYP1A2MAPTALDH1A1
SCHEMBL28616115 0.72 IMPDH2 (0.53) GPR84CYP1A2MAPTALDH1A1MEN1
SCHEMBL434877 0.72 GPR84 (0.64) GPR84HTR2BCYP1A2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109232363-B Synthetic method of 3-selenocyanoindole compound 安徽理工大学 2021-08-13 CN disclosed