Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.64 |
| ▸ | HTR2B | P41595 | 5/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 6/20 | 0.57 |
| ▸ | HTR2C | P28335 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | HTR1A | P08908 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | HTR1D | P28221 | 2/20 | 0.57 |
| ▸ | HTR1B | P28222 | 2/20 | 0.57 |
| ▸ | HTR7 | P34969 | 2/20 | 0.57 |
| ▸ | HTR6 | P50406 | 2/20 | 0.57 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL736956 | 1.00 | GPR84 (0.64) | GPR84HTR2BCYP1A2ALDH1A1CYP2C19 | |
| SCHEMBL1120777 | 0.85 | KDM4E (0.60) | GPR84HTR2BCYP1A2ALDH1A1CYP2C19 | |
| SCHEMBL5432612 | 0.82 | GPR84 (0.66) | GPR84HTR2BCYP1A2ALDH1A1CYP2C19 | |
| SCHEMBL3629976 | 0.81 | HTR2B (0.65) | GPR84HTR2BCYP1A2ALDH1A1CYP2C19 | |
| SCHEMBL28337310 | 0.81 | GPR84 (0.64) | GPR84HTR2BCYP1A2ALDH1A1CYP2C19 | |
| SCHEMBL23259474 | 0.80 | HTR1B (0.52) | GPR84HTR2BCYP1A2CYP2C19HTR2A | |
| SCHEMBL6290566 | 0.79 | GPR84 (0.62) | GPR84HTR2BCYP1A2ALDH1A1CYP2C19 | |
| SCHEMBL21256024 | 0.79 | GPR84 (0.62) | GPR84HTR2BCYP1A2ALDH1A1CYP2C19 | |
| SCHEMBL21623872 | 0.79 | GPR84 (0.62) | GPR84HTR2BCYP1A2ALDH1A1CYP2C19 | |
| SCHEMBL4475932 | 0.79 | GPR84 (0.62) | GPR84HTR2BCYP1A2ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110845547-B | Chiral bidentate ligand, catalyst, preparation method and application thereof | 江苏医药职业学院 | 2021-11-12 | — | — | CN | claimed |
| CN-110845547-A | Chiral bidentate ligand, catalyst, preparation method and application thereof | 江苏医药职业学院 | 2020-02-28 | — | — | CN | claimed |
| EP-1486207-A2 | Sulfonated amino acid derivatives and metalloproteinase inhibitors containing the same | SHIONOGI & CO., LTD. (JP) | 2004-12-15 | — | — | EP | claimed |
| US-20030225043-A1 | Sulfonated amino acid derivatives and metalloproteinase inhibitors containing the same | SHIONOGI & CO., LTD. | 2003-12-04 | — | — | US | claimed |
| US-20030139379-A1 | Sulfonated amino acid derivatives and metalloproteinase inhibitors containing the same | SHIONOGI & CO., LTD. | 2003-07-24 | — | — | US | claimed |
| EP-0950656-A1 | SULFONATED AMINO ACID DERIVATIVES AND METALLOPROTEINASE INHIBITORS CONTAINING THE SAME | SHIONOGI & CO., LTD. (JP) | 1999-10-20 | — | — | EP | claimed |
| US-4199512-A | Compounds for alleviating hypertension | E. R. SQUIBB & SONS, INC. (US) | 1980-04-22 | — | — | US | claimed |
| US-20250195471-A1 | ASYMMETRIC ALLYL TRYPTAMINES | ALEXANDER SHULGIN RES INSTITUTE INC (US) | 2025-06-19 | — | — | US | disclosed |
| US-12239632-B2 | Asymmetric allyl tryptamines | ALEXANDER SHULGIN RESEARCH INSTITUTE, INC. (US) | 2025-03-04 | — | — | US | disclosed |
| US-20240277665-A1 | ASYMMETRIC ALLYL TRYPTAMINES | ALEXANDER SHULGIN RESEARCH INSTITUTE, INC. | 2024-08-22 | — | — | US | disclosed |
| WO-2024158872-A1 | 1,3-INDOLE-PROPANAMIDE INHIBITORS OF SARS-COV-2 PLPRO/NSP3 AND DERIVATIVES THEREOF | THE ROCKEFELLER UNIVERSITY (US) | 2024-08-02 | — | — | WO | disclosed |
| EP-4396162-A2 | ASYMMETRIC ALLYL TRYPTAMINES | Alexander Shulgin Research Institute, Inc. (US) | 2024-07-10 | — | — | EP | disclosed |
| EP-3405477-B1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2023-06-07 | — | — | EP | disclosed |
| US-4294757-A | BLEACHING CELLULOSE FIBERS AND ADDITION OF ALKALI METAL POLYPHOSPHATES AND ALKALI METAL DIETHYLENETRIAMINE PENTA(METHYLENE PHOSPHONAT) | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1981-10-13 | — | — | US | disclosed |
| US-4260608-A | ANTIMICROBIAL, ANTIMITOTIC, AND ANTITUMOR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-04-07 | — | — | US | disclosed |
| US-4256746-A | ANTITUMOR AGENTS; MICROBIOCIDES; MITOSIS | TAKEDA CHEMICAL INDUSTRIES (JP) | 1981-03-17 | — | — | US | disclosed |
| EP-0014402-A1 | Novel 20-0-acylmaytansinoids, process for their preparation and pharmaceutical compositions containing them | Takeda Chemical Industries, Ltd. (JP) | 1980-08-20 | — | — | EP | disclosed |
| EP-0011276-A1 | Maytansinoids, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1980-05-28 | — | — | EP | disclosed |
| EP-0011277-A1 | Dechloromaytansinoids, their production and use and pharmaceutical compositions containing them | Takeda Chemical Industries, Ltd. (JP) | 1980-05-28 | — | — | EP | disclosed |
| EP-0004466-A1 | Demethyl maytansinoids and methods for producing them | Takeda Chemical Industries, Ltd. (JP) | 1979-10-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12239632-B2 | Asymmetric allyl tryptamines | TPH2, TPH1, HTR2A | GPR84 196/4885HTR2B 19/4885CYP1A2 351/4885 |
| US-20250195471-A1 | ASYMMETRIC ALLYL TRYPTAMINES | TPH2, TPH1, HTR2A | GPR84 196/4885HTR2B 19/4885CYP1A2 351/4885 |
| US-20030139379-A1 | Sulfonated amino acid derivatives and metalloproteinase inhibitors containing the same | MMP9, MMP2, MMP1 | GPR84 2375/4885HTR2B 3070/4885CYP1A2 1462/4885 |
| US-20240277665-A1 | ASYMMETRIC ALLYL TRYPTAMINES | TPH2, TPH1, HTR2A | GPR84 196/4885HTR2B 19/4885CYP1A2 351/4885 |
| US-20030225043-A1 | Sulfonated amino acid derivatives and metalloproteinase inhibitors containing the same | MMP9, MMP2, MMP1 | GPR84 2375/4885HTR2B 3070/4885CYP1A2 1462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.