Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.60 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2685329 | 0.85 | KCNK9 (0.67) | KCNK9TP53HDAC8HDAC6KCNK3 | |
| SCHEMBL7302565 | 0.79 | KCNK9 (0.76) | KCNK9TP53HDAC8HDAC6HDAC3 | |
| SCHEMBL7302861 | 0.79 | NPC1 (0.70) | KCNK9TP53HDAC8HDAC6KCNK3 | |
| SCHEMBL7295509 | 0.79 | KCNK9 (0.80) | KCNK9TP53HDAC8HDAC6KCNK3 | |
| SCHEMBL28917376 | 0.78 | NPC1 (0.60) | TP53HDAC8HDAC6HDAC3HDAC11 | |
| SCHEMBL21588759 | 0.78 | PTGS1 (0.72) | KCNK9TP53HDAC8HDAC6KCNK3 | |
| SCHEMBL21588672 | 0.78 | SMN1; SMN2 (0.76) | KCNK9TP53HDAC8HDAC6KCNK3 | |
| SCHEMBL1291198 | 0.78 | RAB9A (0.73) | KCNK9TP53HDAC8HDAC6KCNK3 | |
| SCHEMBL2908907 | 0.77 | HDAC6 (0.74) | KCNK9TP53HDAC8HDAC6HDAC3 | |
| SCHEMBL14195814 | 0.77 | KCNK9 (0.83) | KCNK9TP53HDAC8HDAC6KCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108863860-B | N-substituted phenyl-3-sulfonyl aminobenzamide compound, preparation thereof and application thereof in resisting breast cancer activity | 温州医科大学 | 2021-08-06 | — | — | CN | claimed |
| CN-108863860-B | N-substituted phenyl-3-sulfonyl aminobenzamide compound, preparation thereof and application thereof in resisting breast cancer activity | 温州医科大学 | 2021-08-06 | — | — | CN | disclosed |