Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.70 |
| ▸ | RAB9A | P51151 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.64 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.64 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.59 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.58 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.58 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.58 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1291198 | 0.99 | RAB9A (0.73) | NPC1RAB9ASMN1; SMN2TP53HDAC8 | |
| SCHEMBL3674558 | 0.84 | KCNK3 (0.71) | NPC1RAB9ASMN1; SMN2TP53KCNK9 | |
| SCHEMBL8363018 | 0.83 | SMN1; SMN2 (0.76) | NPC1RAB9ASMN1; SMN2TP53KCNK9 | |
| SCHEMBL7303572 | 0.83 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2HDAC8HDAC6 | |
| SCHEMBL7302565 | 0.82 | KCNK9 (0.76) | NPC1RAB9ASMN1; SMN2TP53HDAC8 | |
| SCHEMBL2685329 | 0.82 | KCNK9 (0.67) | NPC1RAB9ASMN1; SMN2TP53HDAC8 | |
| SCHEMBL7074245 | 0.82 | RAB9A (0.60) | NPC1RAB9ASMN1; SMN2KCNK9KCNK3 | |
| SCHEMBL31078038 | 0.82 | RORC (0.63) | NPC1RAB9AKCNK9KCNK3MEN1 | |
| SCHEMBL21588672 | 0.81 | SMN1; SMN2 (0.76) | NPC1RAB9ASMN1; SMN2TP53HDAC8 | |
| SCHEMBL21588759 | 0.81 | PTGS1 (0.72) | NPC1RAB9ASMN1; SMN2TP53HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |