Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.57 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.57 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PTPRC | P08575 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3074528 | 0.83 | GPR35 (0.59) | TDP1ALDH1A1TSHRMAPK1GPR35 | |
| SCHEMBL16347621 | 0.82 | TSHR (0.54) | TDP1ALDH1A1TSHRMAPK1GPR35 | |
| SCHEMBL11822059 | 0.82 | TSHR (0.52) | TDP1ALDH1A1TSHRMAPK1GPR35 | |
| Acetophenone SCHEMBL6039972 | 0.81 | ALDH1A1 (0.56) | ALDH1A1TSHRMAPK1GPR35TP53 | |
| SCHEMBL1970698 | 0.80 | CASP6 (0.39) | TDP1ALDH1A1TSHRMAPK1GPR35 | |
| SCHEMBL29809877 | 0.79 | TDP1 (0.68) | TDP1ALDH1A1TSHRMAPK1GPR35 | |
| SCHEMBL600206 | 0.79 | TDP1 (0.68) | TDP1ALDH1A1TSHRMAPK1GPR35 | |
| SCHEMBL5958796 | 0.77 | TDP1 (0.65) | TDP1ALDH1A1TSHRMAPK1GPR35 | |
| SCHEMBL2036497 | 0.77 | ALDH1A1 (0.57) | TDP1ALDH1A1TSHRMAPK1GPR35 | |
| SCHEMBL489333 | 0.77 | S100A4 (0.49) | TDP1ALDH1A1TSHRMAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 312 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116675858-A | Preparation method of amino-terminated hyperbranched polythioether and prepared internal crosslinking modified polyurethane | 扬州市祥华新材料科技有限公司 | 2023-09-01 | — | — | CN | claimed |
| CN-111655791-B | Pest and ice phobic compositions with fluid additives | HRL实验室有限责任公司 | 2022-11-04 | — | — | CN | claimed |
| CN-111655791-A | Pest and ice phobic compositions with fluid additives | HRL实验室有限责任公司 | 2020-09-11 | — | — | CN | claimed |
| US-9815809-B2 | Formation of chiral 4-chromanones using chiral pyrrolidines in the presence of phenols or thiophenols | DSM IP ASSETS B.V. (NL) | 2017-11-14 | — | — | US | claimed |
| EP-3016940-B1 | FORMATION OF CHIRAL 4-CHROMANONES USING CHIRAL PYRROLIDINES IN THE PRESENCE OF PHENOLS OR THIOPHENOLS | DSM IP ASSETS BV (NL) | 2017-04-12 | — | — | EP | claimed |
| US-20160168111-A1 | FORMATION OF CHIRAL 4-CHROMANONES USING CHIRAL PYRROLIDINES IN THE PRESENCE OF PHENOLS OR THIOPHENOLS | DSM IP ASSETS B.V. (NL) | 2016-06-16 | — | — | US | claimed |
| EP-1514542-B1 | Medicinal composition comprising Tacrine or Donepezil for improving brain function. | TOYAMA CHEMICAL CO LTD (JP) | 2012-02-22 | — | — | EP | claimed |
| US-5120746-A | Inhibit gastric acid secretion | TOYAMA CHEMICAL CO., LTD. (JP) | 1992-06-09 | — | — | US | claimed |
| US-4643849-A | ANTIULCER, ANTISECRETORY AGENTS | TOYAMA CHEMICAL CO., LTD. (JP) | 1987-02-17 | — | — | US | claimed |
| US-4308380-A | 2-Lower alkyl-2 or 3-cephem-4-carboxylic acid derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-12-29 | — | — | US | claimed |
| US-4267340-A | BACTERICIDES; SYNTHESIS OF PENICILLINS AND CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-05-12 | — | — | US | claimed |
| US-4009159-A | PENICILLINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-02-22 | — | — | US | claimed |
| US-3993646-A | Process for the ring expansion of penicillins to cephalosporin compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-11-23 | — | — | US | claimed |
| US-3978063-A | 1,2,3,4-Tetrahydroisoquinoline derivatives and the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-08-31 | — | — | US | claimed |
| CN-117813357-A | Phase separated antimicrobial coatings and methods of making and using the same | HRL实验室有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-116410114-B | 4-nitrobenzene sulfur chlorine amino protecting group and preparation method thereof | 南开大学 | 2024-02-27 | — | — | CN | disclosed |
| WO-2023249436-A1 | TRANSITION METAL COMPLEX AND ELECTROCHEMILUMINESCENCE-BASED HYDROGEN SULFIDE DETECTION SENSOR INCLUDING SAME | 한국과학기술연구원 | 2023-12-28 | — | — | WO | disclosed |
| US-3954732-A | BACTERICIDAL PENICILLINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-05-04 | — | — | US | disclosed |
| US-3952064-A | FROM PHENOL AND SULFUR CHLORIDE, HYDROGEN CHLORIDE CATALYST | CROWN ZELLERBACH CORPORATION (US) | 1976-04-20 | — | — | US | disclosed |
| US-3948934-A | 2-(Nitromethylene)-1,3-diazacycloalkane insect control agents | SHELL OIL COMPANY (US) | 1976-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168111-A1 | FORMATION OF CHIRAL 4-CHROMANONES USING CHIRAL PYRROLIDINES IN THE PRESENCE OF PHENOLS OR THIOPHENOLS | CYP4B1, CYP4F3, CYP4F2 | TDP1 2015/4885ALDH1A1 986/4885TSHR 2008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.