Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9160393 | 0.79 | NFE2L2 (0.39) | KMT2AMEN1MAPTNPSR1NPC1 | |
| SCHEMBL28361132 | 0.79 | PTGS1 (0.47) | FBP1 | |
| SCHEMBL9160388 | 0.79 | NFE2L2 (0.39) | KMT2AMEN1MAPTNPSR1NPC1 | |
| SCHEMBL10601204 | 0.79 | APP (0.39) | KMT2AMEN1MAPTNPC1ALDH1A1 | |
| SCHEMBL10601208 | 0.79 | APP (0.39) | KMT2AMEN1MAPTNPC1ALDH1A1 | |
| SCHEMBL9157362 | 0.79 | TRPA1 (0.32) | ALDH1A1 | |
| SCHEMBL9157356 | 0.79 | TRPA1 (0.32) | ALDH1A1 | |
| SCHEMBL10416173 | 0.78 | FBP1 (0.44) | KMT2AMEN1MAPTNPSR1NPC1 | |
| SCHEMBL10416172 | 0.78 | FBP1 (0.44) | KMT2AMEN1MAPTNPSR1NPC1 | |
| SCHEMBL28361296 | 0.77 | ALDH1A1 (0.46) | LMNAKMT2AMEN1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113372275-B | Synthetic method of 3, 5-diaryl-4-trifluoromethyl pyrazole derivative | 温州大学 | 2022-09-13 | — | — | CN | disclosed |
| CN-113372275-A | Synthetic method of 3, 5-diaryl-4-trifluoromethyl pyrazole derivative | 温州大学 | 2021-09-10 | — | — | CN | disclosed |