Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9157356 | 1.00 | TRPA1 (0.32) | TRPA1ALDH1A1TSHRCES2CES1 | |
| SCHEMBL28361040 | 0.81 | ALDH1A1 (0.41) | ALDH1A1TSHR | |
| SCHEMBL28618192 | 0.79 | LMNA (0.36) | ALDH1A1 | |
| SCHEMBL9154249 | 0.78 | TRPA1 (0.39) | TRPA1ALDH1A1TSHRCES2CES1 | |
| SCHEMBL10601204 | 0.75 | APP (0.39) | ALDH1A1 | |
| SCHEMBL9160393 | 0.75 | NFE2L2 (0.39) | ALDH1A1 | |
| SCHEMBL9160388 | 0.75 | NFE2L2 (0.39) | ALDH1A1 | |
| SCHEMBL10601208 | 0.75 | APP (0.39) | ALDH1A1 | |
| SCHEMBL28361132 | 0.75 | PTGS1 (0.47) | CES2CES1 | |
| SCHEMBL8731275 | 0.74 | TRPA1 (0.39) | TRPA1ALDH1A1TSHRCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0391390-B1 | Pyridazinones having insecticidal and acaricidal activity and compositions containing them | MINI RICERCA SCIENT TECNOLOG (IT) | 1995-02-08 | — | — | EP | disclosed |
| US-5169848-A | Insecticides, miticides | PRESIDENZA DEL CONSIGLIO DEI MINISTRI-UFFICIO DEL MINISTRO PER IL COORDINAMENTO DELLE INIZIATIVE PER LA RICERVA SCIENTIFICA E TECNOLOGICA (IT) | 1992-12-08 | — | — | US | disclosed |
| EP-0391390-A1 | Pyridazinones having insecticidal and acaricidal activity and compositions containing them | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1990-10-10 | — | — | EP | disclosed |