Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL384843 | 0.84 | CA12 (0.34) | NPC1 | |
| Imidazole SCHEMBL28776214 | 0.70 | ALDH1A1 (0.56) | ALDH1A1FKBP5 | |
| Imidazole SCHEMBL28248513 | 0.69 | ALDH1A1 (0.54) | ALDH1A1FKBP5 | |
| Imidazole SCHEMBL27674379 | 0.68 | ALDH1A1 (0.52) | ALDH1A1FKBP5NPC1 | |
| Imidazole SCHEMBL27749802 | 0.67 | ALDH1A1 (0.56) | ALDH1A1FKBP5NPC1 | |
| Phthalic Anhydride SCHEMBL15568926 | 0.66 | TDP1 (0.54) | ALDH1A1FKBP5NPC1 | |
| SCHEMBL2044670 | 0.65 | PDE3B (0.36) | NPC1 | |
| SCHEMBL7850857 | 0.65 | MAPK14 (0.34) | NPC1 | |
| SCHEMBL24631376 | 0.65 | PTPRC (0.37) | — | |
| SCHEMBL813060 | 0.63 | MAOA (0.59) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113135930-B | Furopyridone imidazole compound, preparation method and application thereof | 上海济煜医药科技有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-113135930-A | Furopyridone imidazole compound and preparation method and application thereof | 上海济煜医药科技有限公司 | 2021-07-20 | — | — | CN | disclosed |