Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 10/20 | 0.37 |
| ▸ | RORA | P35398 | 3/20 | 0.37 |
| ▸ | LGMN | Q99538 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23632046 | 0.88 | PSIP1 (0.39) | RORCRORAGAALMNAHTT | |
| SCHEMBL28619569 | 0.86 | RORC (0.39) | RORCRORAGAALMNAHTT | |
| SCHEMBL23632129 | 0.86 | RORC (0.39) | RORCRORAGAALMNAHTT | |
| SCHEMBL29287120 | 0.84 | RORC (0.39) | RORCRORALMNAHTT | |
| SCHEMBL28607512 | 0.83 | GAA (0.41) | RORCRORAGAAALDH1A1LMNA | |
| SCHEMBL28607513 | 0.83 | GAA (0.41) | RORCRORAGAAALDH1A1LMNA | |
| SCHEMBL27816303 | 0.82 | UTS2R (0.44) | ALDH1A1LMNA | |
| SCHEMBL29287118 | 0.75 | SLC6A9 (0.37) | RORC | |
| SCHEMBL28302130 | 0.73 | RORC (0.39) | RORCRORAGAAALDH1A1LMNA | |
| SCHEMBL28620442 | 0.73 | CA2 (0.43) | RORCRORALGMNALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121463-A | Amide compound with bicyclic structure and application thereof in medicines | 广东东阳光药业有限公司 | 2021-07-16 | — | — | CN | disclosed |
| CN-113072542-A | ROR gamma t inhibitor and preparation method and application thereof | 广东东阳光药业有限公司 | 2021-07-06 | — | — | CN | disclosed |