Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 14/20 | 0.39 |
| ▸ | RORA | P35398 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28619569 | 1.00 | RORC (0.39) | RORCRORALMNAHTTPSEN1 | |
| SCHEMBL23632046 | 0.88 | PSIP1 (0.39) | RORCRORALMNAHTTGAA | |
| SCHEMBL29287118 | 0.88 | SLC6A9 (0.37) | RORC | |
| SCHEMBL29287120 | 0.87 | RORC (0.39) | RORCRORALMNAHTTPSEN1 | |
| SCHEMBL28620441 | 0.86 | RORC (0.37) | RORCRORALMNAHTTGAA | |
| SCHEMBL29287129 | 0.83 | GCK (0.37) | — | |
| SCHEMBL28995697 | 0.82 | RAB9A (0.40) | LMNA | |
| SCHEMBL28821222 | 0.82 | TSHR (0.42) | LMNAGAA | |
| SCHEMBL28404198 | 0.81 | KMT2A (0.43) | LMNAHTT | |
| SCHEMBL27674503 | 0.81 | LMNA (0.39) | LMNAHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021139595-A1 | RORγT INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 东莞市东阳光新药研发有限公司 | 2021-07-15 | — | — | WO | disclosed |