SCHEMBL2862084

SCHEMBL2862084

CCCCSc1cc2c3cc(SCCCC)c(SCCCC)cc3c3cc(SCCCCCCCCCCCCCCCCCC[Si](Cl)(Cl)Cl)c(SCCCC)cc3c2cc1SCCCC

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ TLR8 Q9NR97 1/20 0.37
▸ GPR84 Q9NQS5 8/20 0.36
▸ PTGS2 P35354 4/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ THRB P10828 1/20 0.34
▸ USP2 O75604 1/20 0.34
▸ HSD17B10 Q99714 1/20 0.34
▸ SCN9A Q15858 2/20 0.33
▸ LMNA P02545 1/20 0.33
▸ PKM P14618 1/20 0.33
▸ SCN5A Q14524 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ FPR1 P21462 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2859051 0.97 GPR84 (0.39) GPR84PTGS2SMN1; SMN2THRBUSP2
SCHEMBL2861736 0.86 CNR2 (0.35) TLR8PTGS2LMNAPKM
SCHEMBL2860389 0.85 CNR2 (0.39) TLR8GPR84PTGS2LMNAPKM
SCHEMBL2859062 0.83 LMNA (0.36) GPR84PTGS2USP2HSD17B10LMNA
SCHEMBL2852404 0.82 PTGS2 (0.38) TLR8GPR84PTGS2SCN9ASCN5A
SCHEMBL2859962 0.82 CNR2 (0.39) TLR8GPR84PTGS2USP2HSD17B10
SCHEMBL10906598 0.82 PTGS2 (0.44) GPR84PTGS2THRBSCN9ASCN5A
SCHEMBL10909011 0.82 PTGS2 (0.44) GPR84PTGS2THRBSCN9ASCN5A
SCHEMBL10909807 0.82 PTGS2 (0.44) GPR84PTGS2THRBSCN9ASCN5A
SCHEMBL10908852 0.82 PTGS2 (0.44) GPR84PTGS2THRBSCN9ASCN5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7758932-B2 Liquid crystal display device and display apparatus RICOH COMPANY, LTD. (JP) 2010-07-20 — — US disclosed
US-20080305280-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY APPARATUS RICOH COMPANY, LTD. 2008-12-11 — — US disclosed
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