Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | VDR | P11473 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28820818 | 0.76 | ALDH1A1 (0.58) | KDM4EKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL14495652 | 0.76 | TSHR (0.43) | KDM4EKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL28504376 | 0.75 | NPC1 (0.57) | KDM4EKMT2ANPC1RAB9APKM | |
| SCHEMBL6589381 | 0.75 | SMN1; SMN2 (0.56) | KDM4EKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL27968001 | 0.74 | VDR (0.48) | KDM4EVDRKMT2AALDH1A1NPC1 | |
| SCHEMBL102893 | 0.74 | KDM4E (0.64) | KDM4EKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL7191387 | 0.73 | VDR (0.50) | KDM4EVDRKMT2AALDH1A1NPC1 | |
| SCHEMBL9675281 | 0.71 | VDR (0.46) | KDM4EVDRKMT2AALDH1A1NPC1 | |
| SCHEMBL28820650 | 0.71 | POLB (0.42) | KDM4EKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL2084256 | 0.71 | VDR (0.52) | KDM4EVDRKMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113402467-B | Synthetic method of flibanserin | 山东汇海医药化工有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-113402467-A | Synthetic method of flibanserin | 山东汇海医药化工有限公司 | 2021-09-17 | — | — | CN | disclosed |