Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29643360 | 0.84 | FFAR1 (0.40) | FFAR1FFAR4ALDH1A1MAPTCASP3 | |
| SCHEMBL28623265 | 0.84 | FFAR1 (0.40) | FFAR1FFAR4ALDH1A1MAPTCASP3 | |
| SCHEMBL15248983 | 0.81 | ALDH1A1 (0.45) | ALDH1A1MAPTKMT2AHTTSMN1; SMN2 | |
| SCHEMBL15988986 | 0.78 | CASP6 (0.57) | ALDH1A1MAPTMEN1HSP90AA1KMT2A | |
| SCHEMBL28760470 | 0.78 | TSHR (0.50) | ALDH1A1CASP3SENP8SENP7SENP6 | |
| SCHEMBL28626042 | 0.78 | ATM (0.50) | FFAR1FFAR4ALDH1A1MAPTCASP3 | |
| SCHEMBL16956496 | 0.77 | VCAM1 (0.46) | ALDH1A1MAPTHTTTTR | |
| SCHEMBL2775290 | 0.76 | CASP3 (0.51) | ALDH1A1MAPTCASP3SENP8SENP7 | |
| SCHEMBL28760471 | 0.74 | AKR1C3 (0.47) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6378337 | 0.73 | MEN1 (0.44) | ALDH1A1MAPTMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113429424-B | Preparation method of [1,2,4] oxadiazino indoline-3-ketone derivative | 华侨大学 | 2022-06-07 | — | — | CN | disclosed |
| CN-113429424-A | Preparation method of [1,2,4] oxadiazino indoline-3-ketone derivative | 华侨大学 | 2021-09-24 | — | — | CN | disclosed |