Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29643360 | 1.00 | FFAR1 (0.40) | FFAR1PTGESSENP8SENP7SENP6 | |
| SCHEMBL28623263 | 0.84 | FFAR1 (0.44) | FFAR1SENP8SENP7SENP6CASP3 | |
| SCHEMBL28626042 | 0.77 | ATM (0.50) | FFAR1SENP8SENP7SENP6CASP3 | |
| SCHEMBL28760470 | 0.77 | TSHR (0.50) | SENP8SENP7SENP6CASP3ALDH1A1 | |
| SCHEMBL28760471 | 0.76 | AKR1C3 (0.47) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL2775290 | 0.75 | CASP3 (0.51) | SENP8SENP7SENP6CASP3GRM5 | |
| SCHEMBL15988986 | 0.74 | CASP6 (0.57) | MEN1KMT2AALDH1A1HSP90AA1MAPT | |
| SCHEMBL31224728 | 0.72 | L3MBTL1 (0.49) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL30963302 | 0.72 | PTGES (0.52) | PTGESMEN1KMT2ANPC1RAB9A | |
| SCHEMBL17403305 | 0.72 | NR4A2 (0.54) | MEN1KMT2ARAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113429424-B | Preparation method of [1,2,4] oxadiazino indoline-3-ketone derivative | 华侨大学 | 2022-06-07 | — | — | CN | claimed |
| CN-113429424-A | Preparation method of [1,2,4] oxadiazino indoline-3-ketone derivative | 华侨大学 | 2021-09-24 | — | — | CN | claimed |
| CN-113429424-B | Preparation method of [1,2,4] oxadiazino indoline-3-ketone derivative | 华侨大学 | 2022-06-07 | — | — | CN | disclosed |
| CN-113429424-A | Preparation method of [1,2,4] oxadiazino indoline-3-ketone derivative | 华侨大学 | 2021-09-24 | — | — | CN | disclosed |