Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SLC25A5 | P05141 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8050743 | 0.80 | MAPT (0.51) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL23768192 | 0.80 | P2RX7 (0.49) | — | |
| SCHEMBL856747 | 0.77 | ACHE (0.56) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL28234149 | 0.77 | RAB9A (0.61) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL29476747 | 0.76 | ACHE (0.51) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL1000380 | 0.76 | ACHE (0.51) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL28616302 | 0.75 | ALDH1A1 (0.64) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL30702212 | 0.75 | MAPT (0.56) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL3948845 | 0.75 | MAPT (0.56) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL5311960 | 0.74 | KMT2A (0.55) | MAPTKDM4EMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108752213-B | Method for preparing alpha-hydroxymethyl-beta-dicarbonyl compound by visible light excited disulfide catalysis | 大连理工大学 | 2021-08-10 | — | — | CN | disclosed |
| CN-108558665-B | Method for preparing alpha-hydroxy-beta-dicarbonyl compound by visible light excited disulfide catalysis | 大连理工大学 | 2021-05-07 | — | — | CN | disclosed |