Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28615591 | 0.89 | CACNA1G (0.43) | ALDH1A1KMT2AMEN1EP300POLB | |
| SCHEMBL28618790 | 0.89 | CACNA1G (0.43) | ALDH1A1KMT2AMEN1EP300POLB | |
| SCHEMBL28619845 | 0.89 | ALDH1A1 (0.41) | ALDH1A1ALDH2ALDH3A1KMT2AMEN1 | |
| SCHEMBL28629450 | 0.84 | MEN1 (0.42) | ALDH1A1KMT2AMEN1EP300POLB | |
| SCHEMBL28615244 | 0.84 | ALDH1A1 (0.43) | ALDH1A1ALDH2ALDH3A1KMT2AMEN1 | |
| SCHEMBL28921726 | 0.84 | MEN1 (0.57) | ALDH1A1KMT2AMEN1HTTEP300 | |
| SCHEMBL28628090 | 0.83 | ALOX5 (0.37) | KMT2AMEN1HTTEP300MAPT | |
| SCHEMBL28626647 | 0.81 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1PTGDR2 | |
| SCHEMBL28922217 | 0.79 | ALDH1A1 (0.39) | ALDH1A1KMT2AMEN1HTTEP300 | |
| SCHEMBL28921723 | 0.78 | ALDH1A1 (0.41) | ALDH1A1ALDH2ALDH3A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200993-A | Synthesis method of oxindole spirodihydrofuran compound | 浙江工业大学 | 2021-08-03 | — | — | CN | disclosed |