Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | ADK | P55263 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28921726 | 0.87 | MEN1 (0.57) | ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL28629450 | 0.85 | MEN1 (0.42) | ALDH1A1MEN1KMT2A | |
| SCHEMBL28615244 | 0.85 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AXIAP | |
| SCHEMBL28615591 | 0.85 | CACNA1G (0.43) | ALDH1A1MEN1KMT2A | |
| SCHEMBL28618790 | 0.85 | CACNA1G (0.43) | ALDH1A1MEN1KMT2A | |
| SCHEMBL28623512 | 0.81 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2APTGDR2 | |
| SCHEMBL28619845 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AXIAP | |
| SCHEMBL12085350 | 0.79 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ACRHBPCRHR2 | |
| SCHEMBL28922217 | 0.77 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2A | |
| SCHEMBL28628090 | 0.75 | ALOX5 (0.37) | MEN1KMT2ACHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200993-A | Synthesis method of oxindole spirodihydrofuran compound | 浙江工业大学 | 2021-08-03 | — | — | CN | disclosed |