Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 2/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28615244 | 0.88 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1EP300 | |
| SCHEMBL28921726 | 0.88 | MEN1 (0.57) | MEN1KMT2AALDH1A1EP300CACNA1G | |
| SCHEMBL28615591 | 0.87 | CACNA1G (0.43) | MEN1KMT2AALDH1A1EP300CACNA1G | |
| SCHEMBL28618790 | 0.87 | CACNA1G (0.43) | MEN1KMT2AALDH1A1EP300CACNA1G | |
| SCHEMBL28626647 | 0.85 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1 | |
| SCHEMBL28623512 | 0.84 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1EP300POLB | |
| SCHEMBL28619845 | 0.83 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1EP300POLB | |
| SCHEMBL28628090 | 0.78 | ALOX5 (0.37) | MEN1KMT2AEP300POLB | |
| SCHEMBL28922217 | 0.77 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1EP300 | |
| SCHEMBL28921723 | 0.72 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1CACNA1GCACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200993-A | Synthesis method of oxindole spirodihydrofuran compound | 浙江工业大学 | 2021-08-03 | — | — | CN | disclosed |