Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.37 |
| ▸ | MMP9 | P14780 | 5/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 2/20 | 0.34 |
| ▸ | MMP13 | P45452 | 2/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4181879 | 1.00 | MMP2 (0.37) | MMP2MMP9EPHX1ALDH1A1HTT | |
| SCHEMBL4183422 | 1.00 | MMP2 (0.37) | MMP2MMP9EPHX1ALDH1A1HTT | |
| SCHEMBL9746020 | 1.00 | MMP2 (0.37) | MMP2MMP9EPHX1ALDH1A1HTT | |
| SCHEMBL10440677 | 1.00 | MMP2 (0.37) | MMP2MMP9EPHX1ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL9852429 | 0.99 | MMP2 (0.36) | MMP2MMP9EPHX1ALDH1A1HTT | |
| SCHEMBL27902585 | 0.99 | MMP2 (0.35) | MMP2MMP9EPHX1ALDH1A1HTT | |
| SCHEMBL28625433 | 0.95 | HPGD (0.33) | EPHX1ALDH1A1HTTSOAT1CES2 | |
| SCHEMBL8780388 | 0.91 | MMP2 (0.36) | MMP2MMP9SOAT1CES2CES1 | |
| SCHEMBL7510602 | 0.89 | SMN1; SMN2 (0.33) | ALDH1A1 | |
| SCHEMBL10429680 | 0.89 | MMP2 (0.40) | MMP2MMP9ALDH1A1SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118318033-A | Cell aggregate comprising pituitary hormone-producing cells and method for producing the same | 住友制药株式会社 | 2024-07-09 | — | — | CN | disclosed |
| CN-118043447-A | Method for preparing cell population containing pituitary tissue and cell population | 住友化学株式会社 | 2024-05-14 | — | — | CN | disclosed |
| CN-111670247-B | Method for preparing cancer spheroids and method for selecting colorectal cancer patients | 京诊断株式会社 | 2024-01-05 | — | — | CN | disclosed |
| CN-106211757-B | Methods of treating metabolic syndrome-related conditions using retinoic acid receptor agonists | 康奈尔大学 | 2022-06-07 | — | — | CN | disclosed |
| CN-106572663-B | Combination therapy for head and neck cancer | 康奈尔大学 | 2020-09-29 | — | — | CN | disclosed |
| US-20090176837-A1 | COMPOUNDS WITH ACTIVITY AT RETINOIC ACID RECEPTORS | SONY CORPORATION (JP) | 2009-07-09 | — | — | US | disclosed |
| EP-1726183-A1 | OPTICALLY CONTROLLED OPTICAL-PATH-SWITCHING-TYPE DATA DISTRIBUTION APPARATUS AND DISTRIBUTION METHOD | Dainichiseika Color & Chemicals Mfg. Co., Ltd. (JP) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005089010-A1 | OPTICALLY CONTROLLED OPTICAL-PATH-SWITCHING-TYPE DATA DISTRIBUTION APPARATUS AND DISTRIBUTION METHOD | DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) | 2005-09-22 | — | — | WO | disclosed |
| EP-0368975-A1 | FLUORINATED BIPHENYLDIOLE DERIVATIVES. | MERCK PATENT GMBH (DE) | 1990-05-23 | — | — | EP | disclosed |
| WO-1989012039-A1 | FLUORINATED BIPHENYLDIOLE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176837-A1 | COMPOUNDS WITH ACTIVITY AT RETINOIC ACID RECEPTORS | RARB, RARA, RARG | MMP2 2497/4885MMP9 2089/4885EPHX1 1201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.