SCHEMBL4183422

SCHEMBL4183422

CCCCCCC1(C(=O)O)C=CC(c2ccccc2)=CC1

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 5/20 0.37
MMP9 P14780 5/20 0.37
EPHX1 P07099 3/20 0.35
ALDH1A1 P00352 1/20 0.35
HTT P42858 1/20 0.35
SOAT1 P35610 2/20 0.35
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
MMP3 P08254 1/20 0.35
MMP8 P22894 2/20 0.34
MMP13 P45452 2/20 0.34
NAAA Q02083 1/20 0.34
OPRM1 P35372 1/20 0.34
OPRD1 P41143 1/20 0.34
OPRK1 P41145 1/20 0.34
OPRL1 P41146 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4181879 1.00 MMP2 (0.37) MMP2MMP9EPHX1ALDH1A1HTT
SCHEMBL9746020 1.00 MMP2 (0.37) MMP2MMP9EPHX1ALDH1A1HTT
SCHEMBL4184929 1.00 MMP2 (0.37) MMP2MMP9EPHX1ALDH1A1HTT
SCHEMBL10440677 1.00 MMP2 (0.37) MMP2MMP9EPHX1ALDH1A1HTT
Hydrochloric Acid SCHEMBL9852429 0.99 MMP2 (0.36) MMP2MMP9EPHX1ALDH1A1HTT
SCHEMBL27902585 0.99 MMP2 (0.35) MMP2MMP9EPHX1ALDH1A1HTT
SCHEMBL28625433 0.95 HPGD (0.33) EPHX1ALDH1A1HTTSOAT1CES2
SCHEMBL8780388 0.91 MMP2 (0.36) MMP2MMP9SOAT1CES2CES1
SCHEMBL7510602 0.89 SMN1; SMN2 (0.33) ALDH1A1
SCHEMBL10429680 0.89 MMP2 (0.40) MMP2MMP9ALDH1A1SOAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105969404-B Liquid crystal aligning agent, liquid crystal alignment film formed by liquid crystal aligning agent and liquid crystal display element 奇美实业股份有限公司 2018-03-23 CN disclosed
CN-105969404-A Liquid crystal aligning agent, liquid crystal alignment film formed by liquid crystal aligning agent and liquid crystal display element 奇美实业股份有限公司 2016-09-28 CN disclosed
CN-105567257-A Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element CHI MEI CORP 2016-05-11 CN disclosed
CN-103571502-B Crystal aligning agent and compound JSR CO., LTD. (JP) 2016-05-04 CN disclosed
CN-103374353-B The manufacture method of crystal aligning agent, liquid crystal orienting film, liquid crystal display device and liquid crystal display device JSR CO., LTD. (JP) 2016-01-20 CN disclosed
CN-103131431-B MATERIALS FOR DISPLAY, crystal aligning agent and liquid crystal display device JSR CO., LTD. (JP) 2015-10-07 CN disclosed
CN-102311739-B The manufacture method of liquid crystal aligning agent, liquid crystal display device and liquid crystal display device JSR CO., LTD. (JP) 2015-09-16 CN disclosed
CN-103788962-A Liquid crystal aligning agent for PSA mode liquid crystal display device, liquid crystal alignment film for PSA mode liquid crystal display device, and the PSA mode liquid crystal display device and manufacturing method thereof JSR CORP 2014-05-14 CN disclosed
CN-103571502-A Liquid crystal aligning agent and compound JSR CORP 2014-02-12 CN disclosed
CN-103525435-A Liquid crystal aligning agent, manufacturing method for liquid crystal display device, liquid crystal alignment film, liquid crystal display device, polymer and carboxylic acid JSR CORP 2014-01-22 CN disclosed
CN-103374353-A Liquid crystal alignment agent, liquid crystal alignment film, liquid crystal display element and manufacturing method for liquid crystal display element JSR CORP 2013-10-30 CN disclosed
CN-103131431-A Display material, liquid crystal alignment agent and liquid crystal display element JSR CORP 2013-06-05 CN disclosed
CN-102311739-A The method of manufacture of liquid crystal aligning agent, liquid crystal display device and liquid crystal display device JSR CORP 2012-01-11 CN disclosed
US-20090176837-A1 COMPOUNDS WITH ACTIVITY AT RETINOIC ACID RECEPTORS SONY CORPORATION (JP) 2009-07-09 US disclosed
EP-1907347-A2 COMPOUNDS WITH ACTIVITY AT RETINOIC ACID RECEPTORS Arcadia Pharmaceuticals Inc. (US) 2008-04-09 EP disclosed
WO-2007009083-A2 COMPOUNDS WITH ACTIVITY AT RETINOIC ACID RECEPTORS ACADIA PHARMACEUTICALS INC. (US) 2007-01-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090176837-A1 COMPOUNDS WITH ACTIVITY AT RETINOIC ACID RECEPTORS RARB, RARA, RARG MMP2 2497/4885MMP9 2089/4885EPHX1 1201/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.