Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28625433 | 0.92 | HPGD (0.33) | SMN1; SMN2L3MBTL1HPGDKDM4EALDH1A1 | |
| SCHEMBL27902585 | 0.91 | MMP2 (0.35) | ALDH1A1 | |
| SCHEMBL4183422 | 0.89 | MMP2 (0.37) | ALDH1A1 | |
| SCHEMBL10440677 | 0.89 | MMP2 (0.37) | ALDH1A1 | |
| SCHEMBL4184929 | 0.89 | MMP2 (0.37) | ALDH1A1 | |
| SCHEMBL9746020 | 0.89 | MMP2 (0.37) | ALDH1A1 | |
| SCHEMBL4181879 | 0.89 | MMP2 (0.37) | ALDH1A1 | |
| SCHEMBL2157193 | 0.88 | SMN1; SMN2 (0.33) | SMN1; SMN2L3MBTL1HPGDMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL9852429 | 0.88 | MMP2 (0.36) | ALDH1A1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL4459328 | 0.82 | SRR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773249-A | Compounds, pharmaceutical compositions and methods for treating inflammatory diseases | 艾匹克治疗公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-112029514-B | Polymer-stabilized blue-phase liquid crystal composition and preparation method thereof | 清华大学 | 2021-11-30 | — | — | CN | disclosed |
| CN-112029514-A | Polymer-stabilized blue-phase liquid crystal composition and preparation method thereof | 清华大学 | 2020-12-04 | — | — | CN | disclosed |
| EP-1237849-A1 | ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE | UNIVERSITY COLLEGE LONDON (GB) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001032604-A1 | ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE | UNIVERSITY COLLEGE LONDON (GB) | 2001-05-10 | — | — | WO | disclosed |