SCHEMBL28626002

SCHEMBL28626002

O=C1OC2(c3ccc(O)cc3Oc3c2cc(Cl)c(O)c3Cl)c2ccccc21

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 8/20 0.70
MAPT P10636 4/20 0.70
MEN1 O00255 4/20 0.70
KMT2A Q03164 4/20 0.70
TDP1 Q9NUW8 3/20 0.70
RECQL P46063 2/20 0.70
BLM P54132 2/20 0.70
PRMT1 Q99873 2/20 0.70
ACE2 Q9BYF1 2/20 0.70
HTT P42858 2/20 0.70
HPGD P15428 2/20 0.70
CYP2C19 P33261 1/20 0.70
SMAD3 P84022 1/20 0.70
LMNA P02545 3/20 0.53
GPR55 Q9Y2T6 2/20 0.53
ALOX12 P18054 2/20 0.53
POLB P06746 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
GNG2 P59768 1/20 0.50
GNB1 P62873 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL498286 0.88 MEN1 (0.61) FTOMAPTMEN1KMT2ATDP1
SCHEMBL29486978 0.88 MEN1 (0.61) FTOMAPTMEN1KMT2ATDP1
SCHEMBL14962996 0.87 FTO (0.64) FTOMAPTMEN1KMT2ATDP1
SCHEMBL8607854 0.86 FTO (0.73) FTOMAPTMEN1KMT2ATDP1
SCHEMBL3624632 0.84 GNG2 (0.65) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL28633518 0.83 FTO (0.94) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL29371199 0.83 FTO (1.00) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL29388667 0.83 FTO (1.00) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL16533 0.83 FTO (1.00) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL30272223 0.83 FTO (1.00) FTOMAPTMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113302493-A High specificity and sensitivity immunoadsorption diagnostic assay for simultaneous resolution of multiple antibody isotypes 小利兰·斯坦福大学托管委员会 2021-08-24 CN disclosed