Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | PKLR | P30613 | 1/20 | 0.55 |
| ▸ | RORC | P51449 | 2/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24286266 | 0.91 | PKM (0.57) | NR1H3PKMPKLRRORCNR1H2 | |
| SCHEMBL28614471 | 0.87 | NR1H3 (0.61) | NR1H3PKMPKLRRORCNR1H2 | |
| SCHEMBL30110984 | 0.86 | PKM (0.62) | NR1H3PKMPKLRRORCNR1H2 | |
| SCHEMBL24286271 | 0.84 | PKM (0.54) | NR1H3PKMPKLRRORCNR1H2 | |
| SCHEMBL28627883 | 0.84 | NR1H3 (0.59) | NR1H3PKMPKLRRORCNR1H2 | |
| SCHEMBL24286390 | 0.80 | PKM (0.57) | NR1H3PKMPKLRRORCCYP11B1 | |
| SCHEMBL30660967 | 0.79 | L3MBTL1 (0.49) | NR1H3PKMPKLRRORCNR1H2 | |
| SCHEMBL22278404 | 0.79 | L3MBTL1 (0.49) | NR1H3PKMPKLRRORCNR1H2 | |
| SCHEMBL24286727 | 0.77 | PKM (0.53) | NR1H3PKMPKLRRORCCYP11B1 | |
| SCHEMBL24286545 | 0.77 | RORC (0.62) | NR1H3PKMPKLRRORCCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121463-A | Amide compound with bicyclic structure and application thereof in medicines | 广东东阳光药业有限公司 | 2021-07-16 | — | — | CN | disclosed |