Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28195733 | 0.89 | GCGR (0.39) | MAPTALDH1A1GAANPC1IDO1 | |
| SCHEMBL28195676 | 0.88 | MAPT (0.45) | MAPTALDH1A1GAAKIF11SCN2A | |
| SCHEMBL28636889 | 0.86 | TRPV1 (0.47) | MAPTALDH1A1GAAIDO1KIF11 | |
| SCHEMBL28195673 | 0.86 | KIF11 (0.33) | MAPTALDH1A1GAAKIF11SCN2A | |
| SCHEMBL28646823 | 0.86 | ALDH1A1 (0.44) | MAPTALDH1A1IDO1RAB9AKIF11 | |
| SCHEMBL28195066 | 0.86 | SCN2A (0.43) | MAPTALDH1A1IDO1NPBWR1KIF11 | |
| SCHEMBL28195020 | 0.86 | TP53 (0.38) | MAPTRAB9AGSK3BGCGRMAPK14 | |
| SCHEMBL28195069 | 0.85 | MAPT (0.47) | MAPTALDH1A1GAANPC1IDO1 | |
| SCHEMBL28195670 | 0.83 | KIF11 (0.51) | MAPTALDH1A1KIF11GCGRMAPK14 | |
| SCHEMBL28195054 | 0.83 | NPBWR1 (0.39) | IDO1NPBWR1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107625766-B | Application of thiazole compound as antibacterial synergist | 上海医药工业研究院 | 2021-08-31 | — | — | CN | disclosed |