Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28320871 | 0.86 | SMN1; SMN2 (0.45) | SMN1; SMN2HPGDUSP2ALOX15TSHR | |
| SCHEMBL28320873 | 0.84 | ALDH1A1 (0.43) | SMN1; SMN2HPGDALOX15MAOBALDH1A1 | |
| SCHEMBL28626540 | 0.83 | MPO (0.42) | SMN1; SMN2HPGDALOX15MPOMAOB | |
| SCHEMBL4821326 | 0.80 | SMN1; SMN2 (0.43) | SMN1; SMN2USP2ALOX15MEN1KMT2A | |
| SCHEMBL28319752 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2HPGDALOX15MEN1KMT2A | |
| SCHEMBL28633248 | 0.72 | MPO (0.42) | SMN1; SMN2HPGDMEN1KMT2APOLB | |
| SCHEMBL18864972 | 0.71 | MAOB (0.58) | SMN1; SMN2HPGDTSHRMAPK1MEN1 | |
| SCHEMBL4073579 | 0.70 | SMN1; SMN2 (0.47) | SMN1; SMN2HPGDUSP2ALOX15TSHR | |
| SCHEMBL4014797 | 0.69 | MAOA (0.59) | SMN1; SMN2HPGDTSHRMAPK1MEN1 | |
| SCHEMBL142523 | 0.68 | MAOB (0.41) | MAPK1MPOMAOBBACE1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110283179-B | Method for directly constructing indole-fused ring compound | 中国科学技术大学 | 2021-10-01 | — | — | CN | claimed |
| CN-110283179-B | Method for directly constructing indole-fused ring compound | 中国科学技术大学 | 2021-10-01 | — | — | CN | disclosed |