Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PIEZO1 | Q92508 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28319752 | 0.86 | SMN1; SMN2 (0.47) | SMN1; SMN2HPGDALOX15KMT2AMEN1 | |
| SCHEMBL28628458 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2HPGDUSP2ALOX15TSHR | |
| SCHEMBL28633248 | 0.86 | MPO (0.42) | SMN1; SMN2HPGDKMT2AMEN1POLB | |
| SCHEMBL4821326 | 0.82 | SMN1; SMN2 (0.43) | SMN1; SMN2USP2ALOX15KMT2AMEN1 | |
| SCHEMBL28320873 | 0.73 | ALDH1A1 (0.43) | SMN1; SMN2HPGDALOX15MAOBALDH1A1 | |
| SCHEMBL18864972 | 0.73 | MAOB (0.58) | SMN1; SMN2HPGDTSHRMAPK1KMT2A | |
| SCHEMBL9333373 | 0.72 | CYP2C9 (0.43) | SMN1; SMN2HPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL4073579 | 0.72 | SMN1; SMN2 (0.47) | SMN1; SMN2HPGDUSP2ALOX15TSHR | |
| Cyanide SCHEMBL28319714 | 0.72 | PIEZO1 (0.40) | SMN1; SMN2MAPK1KMT2AMEN1MAOB | |
| SCHEMBL4014797 | 0.71 | MAOA (0.59) | SMN1; SMN2HPGDTSHRMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110283179-B | Method for directly constructing indole-fused ring compound | 中国科学技术大学 | 2021-10-01 | — | — | CN | claimed |
| CN-110283179-A | A kind of method of direct construction indoles and cycle compound | 中国科学技术大学 | 2019-09-27 | — | — | CN | claimed |
| CN-110283179-B | Method for directly constructing indole-fused ring compound | 中国科学技术大学 | 2021-10-01 | — | — | CN | disclosed |