Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.42 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28320871 | 0.86 | SMN1; SMN2 (0.45) | MPOSLC6A2SLC6A4SMN1; SMN2KMT2A | |
| SCHEMBL28319752 | 0.84 | SMN1; SMN2 (0.47) | TP53SMN1; SMN2KMT2AHPGDMEN1 | |
| SCHEMBL28626540 | 0.83 | MPO (0.42) | MPONOS2CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL28628458 | 0.72 | SMN1; SMN2 (0.43) | MPOSLC6A2SLC6A4SMN1; SMN2KMT2A | |
| SCHEMBL28320873 | 0.71 | ALDH1A1 (0.43) | TP53SMN1; SMN2HPGDALDH1A1MAOA | |
| SCHEMBL22804940 | 0.71 | MAOB (0.58) | NOS2CYP2D6SLC6A2SLC6A4TP53 | |
| SCHEMBL20872955 | 0.71 | MAOA (0.54) | NOS2CYP2D6SLC6A2SLC6A4TP53 | |
| SCHEMBL31415641 | 0.70 | CYP2A6 (0.49) | NOS2SMN1; SMN2KMT2AHPGDMEN1 | |
| SCHEMBL6122855 | 0.70 | CYP2A6 (0.49) | NOS2SMN1; SMN2KMT2AHPGDMEN1 | |
| SCHEMBL4821326 | 0.69 | SMN1; SMN2 (0.43) | SMN1; SMN2KMT2AMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110283179-B | Method for directly constructing indole-fused ring compound | 中国科学技术大学 | 2021-10-01 | — | — | CN | claimed |
| CN-110283179-B | Method for directly constructing indole-fused ring compound | 中国科学技术大学 | 2021-10-01 | — | — | CN | disclosed |