Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15971711 | 0.80 | TSHR (0.55) | TSHRMAPTALDH1A1 | |
| SCHEMBL677185 | 0.78 | TDP1 (0.59) | LMNACYP1A2NPC1RAB9AMAPT | |
| SCHEMBL16897300 | 0.78 | CES2 (0.50) | CYP1A2NPC1RAB9AMAPTPKM | |
| SCHEMBL11228311 | 0.77 | LMNA (0.58) | LMNATSHRPARP10MAPTALDH1A1 | |
| SCHEMBL248077 | 0.77 | LMNA (0.59) | LMNACYP1A2CYP3A4MAOATSHR | |
| SCHEMBL6228872 | 0.77 | LMNA (0.59) | LMNACYP1A2CYP3A4MAOATSHR | |
| SCHEMBL28437040 | 0.76 | PBRM1 (0.52) | LMNACYP3A4NPC1ALDH1A1F2 | |
| Ammonia Solution, Strong SCHEMBL8998037 | 0.76 | LMNA (0.56) | LMNATSHRPARP10MAPTALDH1A1 | |
| SCHEMBL9860907 | 0.76 | LMNA (0.56) | LMNATSHRPARP10MAPTALDH1A1 | |
| SCHEMBL28396362 | 0.76 | LMNA (0.56) | LMNATSHRPARP10MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109456215-B | Functional diamine monomer with high planarity and containing fluorene or fluorenone structure as well as synthesis method and application thereof | 湖南工业大学 | 2021-10-01 | — | — | CN | claimed |