Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23674810 | 0.82 | CYP19A1 (0.42) | ALDH1A1KDM4ESMN1; SMN2NPC1LMNA | |
| SCHEMBL16050737 | 0.76 | ALDH1A1 (0.49) | ALDH1A1KDM4ETDP1FAAHHTT | |
| SCHEMBL13819982 | 0.74 | TUBB4A (0.57) | ALDH1A1KDM4ETDP1FAAHHTT | |
| SCHEMBL28093430 | 0.71 | HTT (0.57) | ALDH1A1KDM4ETDP1FAAHHTT | |
| SCHEMBL17137805 | 0.70 | POLB (0.54) | ALDH1A1KDM4ETDP1FAAHHTT | |
| SCHEMBL23674724 | 0.70 | CHRNB2 (0.45) | ALDH1A1TDP1CYP1A2CYP2D6 | |
| SCHEMBL5407250 | 0.67 | KDM4E (0.58) | ALDH1A1KDM4ETDP1HTTHPGD | |
| SCHEMBL13702605 | 0.67 | TUBB4A (0.58) | ALDH1A1KDM4EHTTHPGDTUBB4A | |
| SCHEMBL8896665 | 0.67 | TSHR (0.55) | ALDH1A1KDM4ETDP1HTTHPGD | |
| SCHEMBL6499571 | 0.66 | ALDH1A1 (0.75) | ALDH1A1KDM4ETDP1FAAHHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105980386-B | Pyrazolo compounds and uses thereof | 基因泰克公司 | 2021-08-13 | — | — | CN | disclosed |