Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8149064 | 0.83 | SLC6A4 (0.51) | SLC6A4SLC6A2SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL25669530 | 0.80 | HTR6 (0.53) | SLC6A4SLC6A2SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL18230006 | 0.79 | SLC6A4 (0.50) | SLC6A4SLC6A2SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL6035134 | 0.78 | AOC1 (0.59) | SLC6A4SLC6A2SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL937666 | 0.78 | LOXL2 (0.57) | SLC6A4SLC6A2SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL12344041 | 0.78 | SLC6A4 (0.54) | SLC6A4SLC6A2SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL214076 | 0.76 | — | — | |
| SCHEMBL28983721 | 0.75 | CHRNB2 (0.43) | SLC6A4SLC6A2SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL28628837 | 0.75 | ALDH1A1 (0.39) | LMNAALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL21674093 | 0.75 | ALDH1A1 (0.49) | SLC6A4SLC6A2SLC6A3LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2210881-A1 | Derivatives of syringolin A | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2010-07-28 | — | — | EP | disclosed |