Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 11/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.35 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24193348 | 0.84 | CRHBP (0.38) | MAPTNPC1ALDH1A1TP53HPGD | |
| SCHEMBL27847944 | 0.76 | ATM (0.40) | ATMSIRT1SIRT2LMNAHTT | |
| SCHEMBL442707 | 0.73 | ATM (0.50) | ATMSIRT1SIRT2LMNASIRT3 | |
| SCHEMBL13783751 | 0.70 | LMNA (0.44) | MAPTNPC1ALDH1A1TP53HPGD | |
| SCHEMBL9281031 | 0.69 | ATM (0.50) | ATMSIRT1SIRT2MAPTLMNA | |
| SCHEMBL31193204 | 0.68 | LMNA (0.36) | MAPTNPC1ALDH1A1TP53HPGD | |
| SCHEMBL9878072 | 0.67 | HTR2A (0.33) | MAPTLMNAKCNE1KCNQ1HSP90AA1 | |
| SCHEMBL11811416 | 0.66 | LMNA (0.38) | ATMSIRT1SIRT2MAPTALDH1A1 | |
| SCHEMBL6344614 | 0.65 | OPRD1 (0.45) | — | |
| SCHEMBL2818050 | 0.64 | KCNE1 (0.49) | ATMKCNE1KCNQ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107660205-B | Heterocyclic compounds as LSD1 inhibitors | 因赛特公司 | 2021-08-27 | — | — | CN | claimed |