Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.30 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13783751 | 0.71 | LMNA (0.44) | HSP90AA1MAPTNPSR1LMNAKCNE1 | |
| SCHEMBL31193204 | 0.69 | LMNA (0.36) | HSP90AA1MAPTNPSR1LMNAKCNE1 | |
| SCHEMBL28629708 | 0.67 | ATM (0.40) | HSP90AA1MAPTNPSR1LMNAKCNE1 | |
| SCHEMBL13821303 | 0.65 | KDM4E (0.34) | MAPTLMNA | |
| SCHEMBL28943133 | 0.65 | CYP2D6 (0.39) | HTR2AMAPTNPSR1LMNA | |
| SCHEMBL24193348 | 0.64 | CRHBP (0.38) | HSP90AA1MAPTNPSR1LMNAABCB1 | |
| SCHEMBL20275983 | 0.63 | KDM4E (0.33) | MAPTLMNA | |
| SCHEMBL4461156 | 0.62 | LMNA (0.54) | MAPTNPSR1LMNA | |
| SCHEMBL24151289 | 0.62 | KCNE1 (0.42) | HTR2ANPSR1LMNAABCB1KCNE1 | |
| SCHEMBL13752382 | 0.62 | CA2 (0.43) | MAPTNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429535-A1 | FUNGICIDAL BENZODIOXANE AMINE DERIVATIVES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-06-05 | — | — | EP | disclosed |
| EP-0359400-A1 | Fungicidal benzodioxane amine derivatives | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-03-21 | — | — | EP | disclosed |
| WO-1990002122-A1 | FUNGICIDAL BENZODIOXANE AMINE DERIVATIVES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-03-08 | — | — | WO | disclosed |