Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.42 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2862979 | 0.89 | TRPV1 (0.44) | TRPV1P2RY1P2RY14SMN1; SMN2 | |
| SCHEMBL2848538 | 0.82 | MAPT (0.45) | TRPV1SMN1; SMN2 | |
| SCHEMBL2856974 | 0.82 | MAPT (0.39) | TRPV1MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL2857337 | 0.81 | KMT2A (0.43) | P2RY1MEN1KMT2AL3MBTL1 | |
| SCHEMBL2855496 | 0.81 | KDM4E (0.46) | MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL2854592 | 0.79 | MEN1 (0.40) | MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL2856976 | 0.78 | MAPT (0.52) | TRPV1SMN1; SMN2 | |
| SCHEMBL2854678 | 0.77 | ATR (0.40) | P2RY1P2RY14NAMPT | |
| SCHEMBL2853241 | 0.77 | SMN1; SMN2 (0.41) | MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL2850388 | 0.77 | LMNA (0.35) | KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |