Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | GPX4 | P36969 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852553 | 0.87 | MALT1 (0.40) | MAPTNPSR1SMN1; SMN2TRPV1MEN1 | |
| SCHEMBL2862979 | 0.85 | TRPV1 (0.44) | SMN1; SMN2GAATRPV1KDM4E | |
| SCHEMBL2854492 | 0.83 | MAPT (0.42) | MAPTNPSR1SMN1; SMN2RAB9AGAA | |
| SCHEMBL2848538 | 0.83 | MAPT (0.45) | MAPTNPSR1SMN1; SMN2RAB9ATRPV1 | |
| SCHEMBL2857917 | 0.83 | MAPT (0.42) | MAPTSMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL2861607 | 0.82 | TRPV1 (0.42) | SMN1; SMN2TRPV1MEN1KMT2AL3MBTL1 | |
| SCHEMBL2862993 | 0.81 | MEN1 (0.41) | MAPTNPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2852401 | 0.80 | L3MBTL1 (0.39) | NPSR1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL2853347 | 0.79 | TRPV1 (0.41) | MAPTTRPV1 | |
| SCHEMBL2852387 | 0.79 | P2RX7 (0.37) | MAPTGAAKEAP1NFE2L2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |