Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28640398 | 0.87 | ALDH1A1 (0.49) | GLAKMT2ASMN1; SMN2NPC1GAA | |
| SCHEMBL28625455 | 0.85 | KDM4E (0.49) | SMN1; SMN2TAAR1NPC1GAARAB9A | |
| SCHEMBL28923423 | 0.84 | CNR1 (0.51) | SMN1; SMN2TAAR1NPC1GAARAB9A | |
| SCHEMBL28631610 | 0.84 | NPC1 (0.48) | SMN1; SMN2TAAR1NPC1GAARAB9A | |
| SCHEMBL16562220 | 0.82 | ALDH1A1 (0.70) | GLAKMT2ASMN1; SMN2TAAR1ALDH1A1 | |
| SCHEMBL28625023 | 0.81 | CYP3A4 (0.47) | SMN1; SMN2GAAALDH1A1POLBMAPT | |
| SCHEMBL16562105 | 0.81 | ALDH1A1 (0.72) | GLAKMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL28622914 | 0.80 | CES2 (0.52) | KMT2ASMN1; SMN2TAAR1NPC1GAA | |
| SCHEMBL4322629 | 0.79 | GLA (0.77) | GLAKMT2ASMN1; SMN2TAAR1NPC1 | |
| SCHEMBL17117344 | 0.75 | SMN1; SMN2 (0.57) | SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641878-B | DIPROVOCIM: effective TLR agonist | 斯克里普斯研究学院 | 2021-09-14 | — | — | CN | disclosed |