Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.43 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.43 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.43 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28625455 | 0.88 | KDM4E (0.49) | ALDH1A1NPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL28630343 | 0.87 | GLA (0.58) | ALDH1A1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28631610 | 0.86 | NPC1 (0.48) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28923423 | 0.86 | CNR1 (0.51) | ALDH1A1TSHRHPGDNPC1RAB9A | |
| SCHEMBL28625023 | 0.83 | CYP3A4 (0.47) | ALDH1A1TSHRHPGDSMN1; SMN2GAA | |
| SCHEMBL28622914 | 0.80 | CES2 (0.52) | ALDH1A1KMT2AMEN1HPGDNPC1 | |
| SCHEMBL20961904 | 0.76 | KMT2A (0.59) | ALDH1A1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL28642116 | 0.74 | TRPV1 (0.45) | ALDH1A1KMT2AMEN1HPGDNPC1 | |
| SCHEMBL5705148 | 0.73 | KMT2A (0.74) | ALDH1A1TSHRKMT2AHPGDNPC1 | |
| SCHEMBL28109095 | 0.72 | NPC1 (0.50) | ALDH1A1KMT2AMEN1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641878-B | DIPROVOCIM: effective TLR agonist | 斯克里普斯研究学院 | 2021-09-14 | — | — | CN | disclosed |