Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | LPL | P06858 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20865747 | 0.82 | LPL (0.37) | LPLLIPG | |
| SCHEMBL21493492 | 0.82 | KIF11 (0.35) | ARLPLLIPGCYP1A2 | |
| SCHEMBL28654934 | 0.80 | LPL (0.33) | LPLLIPG | |
| SCHEMBL19098449 | 0.80 | ESR2 (0.32) | LPLLIPG | |
| SCHEMBL20865722 | 0.79 | MEN1 (0.33) | LPLLIPGMEN1CYP1A2KMT2A | |
| SCHEMBL18189341 | 0.77 | LIPG (0.34) | ARLPLLIPG | |
| SCHEMBL28660659 | 0.77 | CSF1R (0.33) | LPLLIPGMEN1KMT2A | |
| SCHEMBL28658657 | 0.77 | LPL (0.35) | LPLLIPG | |
| SCHEMBL29086753 | 0.70 | ROCK1 (0.31) | LPLLIPG | |
| SCHEMBL12470951 | 0.70 | DRD2 (0.45) | LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107750250-B | Indolone compounds and their use as AMPA receptor modulators | 詹森药业有限公司 | 2021-09-07 | — | — | CN | disclosed |