Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 7/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28654934 | 0.81 | LPL (0.33) | LPLLIPGP2RX7 | |
| SCHEMBL20865722 | 0.80 | MEN1 (0.33) | LPLLIPGP2RX7 | |
| SCHEMBL20865747 | 0.80 | LPL (0.37) | LPLLIPGROCK1P2RX7 | |
| SCHEMBL19098449 | 0.78 | ESR2 (0.32) | LPLLIPGP2RX7 | |
| SCHEMBL28660659 | 0.78 | CSF1R (0.33) | LPLLIPGP2RX7 | |
| SCHEMBL18189371 | 0.78 | LIPG (0.35) | LPLLIPGROCK1GSK3AGSK3B | |
| SCHEMBL28630852 | 0.77 | AR (0.32) | LPLLIPG | |
| SCHEMBL24680853 | 0.71 | HSP90AA1 (0.36) | — | |
| SCHEMBL12470951 | 0.71 | DRD2 (0.45) | LPLLIPGROCK1 | |
| SCHEMBL5899764 | 0.71 | LIPG (0.43) | LPLLIPGROCK1GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109963851-B | Fused bicyclic pyridine compounds and their use as AMPA receptor modulators | 詹森药业有限公司 | 2021-11-30 | — | — | CN | disclosed |