Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.51 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 3/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL28923723 | 1.00 | PLA2G2A (0.66) | PLA2G2ATP53TSHRPLA2G4BSMPD1 | |
| Potassium Ion SCHEMBL28924336 | 0.93 | PLA2G2A (0.56) | PLA2G2ATP53TSHRPLA2G4BRARB | |
| SCHEMBL15955753 | 0.83 | PLA2G2A (0.93) | PLA2G2ATP53TSHRPLA2G4BRARB | |
| SCHEMBL1768821 | 0.83 | PLA2G2A (0.93) | PLA2G2ATP53TSHRPLA2G4BRARB | |
| SCHEMBL1820396 | 0.83 | PLA2G2A (0.93) | PLA2G2ATP53TSHRPLA2G4BRARB | |
| SCHEMBL1768906 | 0.83 | PLA2G2A (0.93) | PLA2G2ATP53TSHRPLA2G4BRARB | |
| SCHEMBL5949309 | 0.81 | PLA2G2A (0.68) | PLA2G2ATP53TSHRPLA2G4BSMPD1 | |
| SCHEMBL4592928 | 0.81 | PLA2G2A (0.68) | PLA2G2ATP53TSHRPLA2G4BSMPD1 | |
| SCHEMBL5948532 | 0.81 | PLA2G2A (0.68) | PLA2G2ATP53TSHRPLA2G4BSMPD1 | |
| Hydrochloric Acid SCHEMBL4592930 | 0.81 | PLA2G2A (0.90) | PLA2G2ATP53TSHRPLA2G4BRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109485573-B | Aromatic dicarboxylic acid ionic liquid and preparation method and application thereof | 宝鸡文理学院 | 2021-04-30 | — | — | CN | disclosed |