Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | GPR39 | O43194 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31294545 | 0.82 | IL1B (0.43) | POLBGPR39GRM4GSK3AMAPK10 | |
| SCHEMBL17700313 | 0.80 | NOS2 (0.56) | NUDT1POLBGPR39NOS2CYP1A2 | |
| SCHEMBL26686386 | 0.79 | EGFR (0.51) | POLBHRH4GRM4GSK3AMAPK10 | |
| SCHEMBL19471908 | 0.76 | POLB (0.44) | POLBGRM4GSK3AMAPK10RIOK2 | |
| SCHEMBL3450728 | 0.75 | NUDT1 (0.65) | NUDT1HRH4HRH3GPR39 | |
| SCHEMBL28625078 | 0.74 | NOS1 (0.39) | POLBGRM4GSK3AMAPK10RIOK2 | |
| SCHEMBL15356370 | 0.73 | HRH4 (0.51) | NUDT1HRH4HRH3GPR39FGFR4 | |
| SCHEMBL29807300 | 0.72 | — | — | |
| SCHEMBL1642983 | 0.72 | — | — | |
| SCHEMBL1833612 | 0.72 | POLB (0.42) | POLBHRH4GRM4GSK3AMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735423-A1 | KV7 MODULATORS | Saniona A/S (DK) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025003343-A1 | KV7 MODULATORS | SANIONA A/S (DK) | 2025-01-02 | — | — | WO | disclosed |
| CN-113200961-A | Heterocyclic inhibitors of ERK1 and ERK2 and their use in the treatment of cancer | 阿沙纳生物科学公司 | 2021-08-03 | — | — | CN | disclosed |