Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | IDH2 | P48735 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GPR39 | O43194 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.37 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | EEF2K | O00418 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.35 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.34 |
| ▸ | BUB1 | O43683 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28632009 | 0.82 | NUDT1 (0.51) | POLBGPR39GRM4GSK3AMAPK10 | |
| SCHEMBL24605491 | 0.79 | MEN1 (0.41) | IL1BNLRP3GPR39RIOK2IRAK4 | |
| SCHEMBL17700712 | 0.79 | MAPK1 (0.48) | IDH2RIOK2PHGDH | |
| SCHEMBL26686808 | 0.79 | IRAK4 (0.35) | IL1BNLRP3IDH2POLBGPR39 | |
| SCHEMBL17700752 | 0.79 | NOS2 (0.54) | POLBPHGDHCYP1A2 | |
| Lithium SCHEMBL30633379 | 0.77 | IRAK4 (0.35) | IL1BNLRP3IDH2POLBGPR39 | |
| SCHEMBL21889142 | 0.76 | ALDH1A1 (0.39) | IL1BNLRP3IDH2RIOK2IRAK4 | |
| SCHEMBL30931701 | 0.76 | LOXL2 (0.55) | — | |
| SCHEMBL17372267 | 0.76 | LOXL2 (0.55) | — | |
| SCHEMBL17371932 | 0.76 | IDH1 (0.41) | CYP1A2KCNH2IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735423-A1 | KV7 MODULATORS | Saniona A/S (DK) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025003343-A1 | KV7 MODULATORS | SANIONA A/S (DK) | 2025-01-02 | — | — | WO | disclosed |