Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1465863 | 0.85 | MAPT (0.48) | MAPTALDH1A1LMNASMN1; SMN2POLB | |
| SCHEMBL1465548 | 0.79 | ALDH1A1 (0.45) | RECQLMAPTALDH1A1POLBKMT2A | |
| SCHEMBL5031380 | 0.77 | RIPK1 (0.50) | RECQLMAPTKDM4EHCAR3ALDH1A1 | |
| SCHEMBL9373869 | 0.73 | RECQL (0.66) | RECQLMAPTKDM4EHCAR3ALDH1A1 | |
| SCHEMBL27510433 | 0.72 | HTT (0.57) | MAPTALDH1A1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL6771507 | 0.72 | MAPT (0.46) | MAPTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9507998 | 0.72 | MAPT (0.54) | MAPTKDM4EHCAR3ALDH1A1LMNA | |
| SCHEMBL13365210 | 0.71 | MAPT (0.48) | RECQLMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL14294847 | 0.70 | MAPT (0.69) | MAPTKDM4EHCAR3ALDH1A1LMNA | |
| SCHEMBL8762394 | 0.69 | ALDH1A1 (0.76) | MAPTKDM4EHCAR3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105693701-B | Modulators of ATP-binding cassette transporters | 弗特克斯药品有限公司 | 2021-08-10 | — | — | CN | disclosed |