Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15341473 | 0.75 | ALOX15 (0.32) | ALDH1A1 | |
| SCHEMBL3053229 | 0.73 | SMN1; SMN2 (0.41) | ALDH1A1MAPTCACNA1BAPBA1 | |
| SCHEMBL873545 | 0.73 | — | — | |
| SCHEMBL7564252 | 0.71 | MAPT (0.34) | ALDH1A1MAPTCACNA1BAPBA1TSHR | |
| SCHEMBL694328 | 0.70 | — | — | |
| SCHEMBL873544 | 0.70 | — | — | |
| SCHEMBL1894433 | 0.70 | — | — | |
| SCHEMBL28510539 | 0.69 | — | — | |
| SCHEMBL463385 | 0.69 | CYP3A4 (0.42) | ALDH1A1MAPTCACNA1BAPBA1CYP3A4 | |
| SCHEMBL16265028 | 0.69 | ALDH1A1 (0.38) | ALDH1A1MAPTCYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113429424-B | Preparation method of [1,2,4] oxadiazino indoline-3-ketone derivative | 华侨大学 | 2022-06-07 | — | — | CN | claimed |
| CN-113429424-A | Preparation method of [1,2,4] oxadiazino indoline-3-ketone derivative | 华侨大学 | 2021-09-24 | — | — | CN | claimed |
| CN-113429424-B | Preparation method of [1,2,4] oxadiazino indoline-3-ketone derivative | 华侨大学 | 2022-06-07 | — | — | CN | disclosed |
| CN-113429424-A | Preparation method of [1,2,4] oxadiazino indoline-3-ketone derivative | 华侨大学 | 2021-09-24 | — | — | CN | disclosed |